Cell Shape Movies and Images

These movies and images can be used for teaching purposes.  Please acknowledge the source as the Vale Lab web site or iBioSeminars.Org.

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GFP Actin: Drosophila S2 cell plated on Con A. Low levels of GFP-actin expression produces a speckled effect that facilitates observation of actin retrograde flow in S2 cells. The cell margins also exhibit periods of extension and retraction, as well as vigorous membrane ruffling.  






(Click images for larger)
Drosophila S2 cells plated on Con A and stained for actin (red), tubulin (green), and DNA (blue). S2 cells dramatically change their morphology when plated on glass coverslips coated with the lectin concanavalin A (con A.  
DRhoGEF2-Mediated Cellular Shape Changes Require Rho1: Three-dimensional reconstructions of a control S2 cell stained with rhodamine-phalloidin and spread on concanavalin A in the x-y (A) and x-z (B) planes reveal tha the cells adopt a discoid shape.
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last updated 9/7/12